Functions of the thyroid gland in the body. What functions does the thyroid gland perform in the human body? Thyroid hormones and features of their biosynthesis.

16.08.2019

Thyroid gland– the largest delicate organ, which has a great influence on the healthy state of the human body, requires careful attention to various manifestations of imbalance in its work, and does not tolerate neglect of its treatment.

The thyroid gland plays a very important role, starting from embryonic development and further at all stages of growth. From normal function thyroid gland depends on the health and comprehensive development of a person.

However, despite the possible benefits, concerns have been raised that soy may be contraindicated in some populations. One of these concerns is that soy may adversely affect thyroid function and interfere with the absorption of synthetic thyroid hormones.

The purpose of this review is to evaluate the relevant literature and provide the basis for clinical guidelines that can help counsel patients about the effects of soy on thyroid function. Was identified in total 14 studies that determined the effects of soy products or isoflavones on at least one marker for thyroid function in healthy volunteers. Eight of them included women, four men, and two men and women. With one exception, no significant effects were observed in these studies.

The thyroid gland has the shape of two petals connected to each other, they lie in front of the trachea. It is easy to find between the thyroid cartilage and the rings (5 – 6) of the trachea.

The size of the gland changes with age:

  • an infant has approximately one gram;
  • adult person from 20 to 30 g;
  • the greatest parameters of the organ are possible at 14 – 17 years;
  • After 45 years, weight decreases due to aging of the body.

The female thyroid gland is slightly smaller than the male thyroid gland. Its size increases during pregnancy. She has two capsules. The external capsule performs the main function of a binding instrument necessary for strong fixation of the organ to the trachea and larynx.

In summary, these studies do not suggest that soy products or isoflavones have a negative effect on thyroid function in people with healthy thyroid function who do not suffer from iodine deficiency. In contrast, some indications indicate that soy products may require an increase in the dose of thyroid hormones by inhibiting thyroid uptake in patients suffering from thyroid dysfunction. However, under thyroid function, polluting adults do not need to avoid soy products.

As a person gets older, its location may change slightly. In children, the thyroid gland is at the same level as the thyroid cartilage, but with age it drops lower. The organ occupies a similar position in sternal goiter.

For the organ to function normally, a significant blood consumption is required. For this reason, it is equipped with an extensive venous and developed arterial system. Therefore, the color of the organ in a healthy state is red-brown. If we compare the intensity of blood flow with other organs, then in the thyroid body the intensity is 50 times greater than in the muscles. Blood flow may increase if ailments occur, which result in a rapid growth rate of hormones.

For this reason, it is important for consumers of soy products to ensure adequate iodine intake. Soy protein is one of those topics that is constantly the subject of debate and controversy, and which causes advocates and opponents of soy products to reliably produce all sorts of seemingly good arguments for the benefits or risks of soy.

From the very beginning, people are vulnerable to extremes, and nowhere does this seem more common than in the health sector. Whenever a nutrient is discovered to be healthy, people without exception believe that they must do better, and they start by using megadoses of that nutrient. This inevitably leads to a backlash when people learn that bigger really isn't better. Then, without exception, they go on a crusade against that nutrient, not realizing that their own extreme behavior is the actual cause of the problem.

Blood is supplied to the thyroid gland using the thyroid arteries, which form anastomoses with each other. When the supplied blood supplies the thyroid tissue with oxygen, it collects waste substances and concentrates in the veins located under the capsule. Venous drainage occurs through the unpaired plexus.

Outflow occurs as a result of the active activity of the venous and lymphatic systems. If pathologies occur, thyroid-stimulating and thyroid-blocking immunoglobulins, as well as antithyroid antibodies, are removed from the gland.

One of my favorite examples is oat bran in the eighties. Having learned that oat bran improves blood fat levels, people began to eat mountains - 50 grams per day or more. People used there dose for horses - you know - better. Until it was discovered that such a massive supply of fiber - especially from isolated sources - can cause vitamin and mineral deficiencies by binding up these nutrients before they can be absorbed.

This brings me to the scope of today's research report on soy protein and thyroid function. As always, there are camps on both sides of the debate that claim soy protein has either positive or negative effects on thyroid hormones. And as always, the truth about how soy protein affects thyroid hormones lies somewhere in the middle and depends on other factors. Today's review will be reviewed.

The thyroid gland can store some types of hormones in the form of droplets, and some may be bound to a carrier protein in the blood.

The thyroid gland has sympathetic and parasympathetic innervation. It is produced in parts nerve fibers the autonomic system of the body, that is, thanks to the threads of the vagus nerve, as well as the fibers of the cervical ganglia. -

Of course, the thyroid gland still controls about a million other things in the body, and an example of this is that low levels T3 can cause depression. There are many other trace elements involved in this transformation process. These include, among others, selenium and iron. Soy protein is known to contain hormone mimetics called phytoestrogens. These include genotypes, daidzein and others. One of them is that there is a lot of controversy regarding the effects of these types of compounds in the human diet. Although phytoestrogens may have some positive effects, other studies show negative effects.


The main functions of the thyroid gland in the body are the production of useful substances from iodine and tyrosine directly into the blood:

  1. Thyroxine or tetraiodothyronine - T4. Helps regulate energy metabolism, protein synthesis, overall growth and normal proportional development of the body from an early age.
  2. Triiodothyronine - T3. Only 20% are reproduced by the organ.
  3. Calcitonin – this thyroid hormone does not contain iodine. Important for regulating the amount of both calcium and phosphorus in the blood. Necessary for implementing impulse sends nerve endings in muscle tissue.

The main intrasecretory activity of the thyroid gland is carried out, that is, the metabolic actions of the body, the activity of the cardiovascular and digestive systems, psycho-emotional and sexual activity are regulated. The functioning of the thyroid gland is very important during early childhood, since the development of brain activity, among other things, depends on its normal activity.

A significant part of the influence of positive or negative influences depends on what you are looking at and of course what dosage you are using. The effects of phytoestrogens are much less studied and known in men. There are likely gender and population responses to these compounds and whether soy has any effect depends largely on the amount consumed. Small amounts of soybeans usually have minimal or no effect on most items tested, while large amounts are often observed.

The entire process of hormonal synthesis is regulated by thyroid-stimulating hormone - TSH, which is produced by the anterior lobe of the pituitary gland. TSH itself receives signals from the thyrotropin-releasing hormone TRH, which is produced by the hypothalamus.

One part of the brain, the pituitary gland, regulates the amount of hormone production, the other part, the hypothalamus, assists the pituitary gland in producing this control. The work is carried out according to the following scheme: the hypothalamus sends information to the pituitary gland, the pituitary gland controls the thyroid gland. The pituitary gland performs a controlling function on the amount of hormones in the blood. If there are not enough hormones, TSH increases, which instructs the gland to increase their synthesis.

Exists old saying in the field of medicine that says the dosage makes the poison, and this is certainly one of those situations. After we've taken the background, the research review, a review paper that examined the effects of soy protein on thyroid hormone status and metabolism, continues.

However, as the paper notes, studies show very different effects in people in whom soy protein has little or no effect on thyroid secretion. This is another example where the results of an animal study do not translate to humans. Of course, there have been studies done with animals that indicate negative influence Soy protein, in particular, has a phytoestrogens effect on thyroid health - something that people seem to ignore about soy when they claim that soy increases thyroid hormone secretion.

All thyroid activity is controlled by the hypothalamus together with the pituitary gland. The hypothalamus produces a substance that monitors the functions of the thyroid gland - thyrotropin-releasing hormone - TRH. When it penetrates the pituitary gland, thyroid-stimulating hormone - TSH is synthesized, which activates the synthesis of T4 and T3. T4 - capable of turning into T3. And T3 is able to activate cellular activity.

Additionally, soy protein appears to have little effect on thyroid health in people with normal thyroid function. The review looked at 14 different studies and, with one exception, were able to observe only a small or even negligible effect of the soy diet on any marker for thyroid hormone status. To reiterate this, no significant effect of soy protein on thyroid hormone status is observed in people with normal thyroid function.

However, soy protein may cause problems in people with pre-existing symptoms of low thyroid function. Research has shown that consuming soy protein may increase the dosage of thyroid hormone medications, and people who must take thyroid hormones should avoid soy protein immediately before or after taking these medications.

When the synthesis of hormones is restored, the pituitary gland stops the production of TSH, returning to normal state, preventing the creation of hyperfunction. If the rhythm is not restored, then treatment is required.

The thyroid gland is involved in important functions:

  1. Controls body temperature.
  2. Regulation of heart rates.
  3. Activates the production of brain cells (especially important at an early age).
  4. Stimulates proportional physical growth and normal development of the body.
  5. Stimulate work nervous system, increases the level of attention and speed of reactions.

The role of the thyroid gland in the human body is so significant for the normal functioning of the human body, so they should not be underestimated.

Article by Lyle MacDonald. Here you can find the text on English. You can find more interesting articles and information about it. Thyroid disease can have many faces. Symptoms are often initially nonspecific, which often complicates diagnosis. If we finally get to the problem, an even more problematic search for causes begins. Why did the body lose control of the thyroid gland? What was annoying small organ so much so that it either works too little or too much or is perhaps chronically inflamed?

The thyroid gland has extremely important functions

And what exactly can be done in this situation to awaken the self-healing ability of the body and especially the thyroid gland? With the balanced production of its thyroid hormones, it controls the metabolism of every single cell in the body as well as the body's energy needs.

Having a small size, it, through the substances it produces, affects almost all life processes:

It regulates heart rhythm as well as heat balance, activates oxygen uptake into cells and tissues, stimulates respiratory and intestinal function, and increases the reactivity of nerve and muscle tissue. Moreover, the thyroid gland plays a crucial role in human development as growth and intelligence are also controlled by it, so thyroid contraction in children leads to severe mental and physical impairment.

Thyroid hormone production

Given these multiple tasks, it is not surprising that the entire body can become out of balance if this important gland is no longer functioning properly. In this disease, the body forms various antibodies, which are faulty in performing their tasks, and on the other hand, completely uncontrollable. Some of them stimulate the hormone-producing cells of the thyroid gland, so that the resulting significantly increased production of hormones inevitably leads to hyperthyroidism.

  1. Its main activity is to support the normal metabolic cycle occurring in cells.
  2. Thyroids are required to create conditions for proportional human development. If there are not enough of them from infancy, then growth is likely to slow down or completely stop, and if there is a deficiency of them during gestation in a woman’s body, it is possible that the baby’s brain will not receive proper development.
  3. The thyroid gland monitors body weight control. If there is an increased food consumption, its activity is activated, that is, the synthesis of T3 increases, which leads to an increase in metabolism. Conversely, if malnutrition occurs, activity decreases and slow metabolism occurs.
  4. The role of the thyroid gland is known healthy condition mammary glands in women.
  5. Without the thyroid gland, the immune system cannot function. With its help, T cells are stimulated, which help the system destroy infections.
  6. The thyroid gland provides important role during the aging of the body.
  7. The thyroid gland affects the water-salt balance and the formation of vitamins (for example, the synthesis of vitamin A by the liver).
  8. Without the thyroid gland, growth hormones do not influence the brain centers.

Substances produced by the thyroid gland help regulate homeostasis, which performs some very important functions:

However, other antibodies falsely treat thyroid tissue as a foreign body that needs to be controlled. As a result, they attack tissue, which can cause severe inflammatory reactions. This explains the fact that Graves' disease is also called an autoimmune disease.

Typical signs of this disease are goiter, as well as more or less pronounced hysteresis eyeballs. In this disease, parts of the thyroid gland suddenly produce uncontrolled hormones without being able to influence the pituitary gland. As a result, an overactive thyroid gland develops. If this is the only network of autonomous cells, then they speak of a so-called “hot node”.

  1. Participates in regulating metabolic processes. Responsible for the structural formation of cells. Monitors the process of cell death (apoptosis).
  2. Thyroid substances control temperature and energy reproduction, that is, they create a calorigenic effect. Due to this, the tissues are saturated with oxygen. Control the presence of free radicals.
  3. Thyroid-stimulating substances develop a person’s mental and physical abilities, as well as his psycho-emotional state. When not enough of them are produced in the baby’s body, development slows down and terrible diseases appear. When a deficiency occurs during pregnancy, cretinism is possible.
  4. Normal activity of the thyroid gland ensures the formation immune system. People gain the opportunity to resist infectious diseases.

Areas outside of this node can also be controlled through the pituitary gland. Unlike a so-called “cold nodule,” in areas where only a few or no hormones are produced, a hot nodule is almost never “cancerous.” On the other hand, cold nodules can change greatly, which can lead to thyroid cancer.

Hashimoto's thyroiditis - chronic thyroiditis

This form of thyroid inflammation, as well as Graves' disease, is an autoimmune disease. At the initial stage of this disease, the body exhibits the typical symptoms of an overactive thyroid gland. In this case, as in the case of Graves' disease, antibodies are formed that attack the thyroid tissue, leading to inflammation of this organ and, ultimately, to the dissolution of the thyroid gland. Hormones stored in inflammatory areas are suddenly released in the initial phase, leading to an overactive thyroid function.